PRO Consortium Workshop 2019

From NCOR Wiki
Revision as of 20:55, 19 August 2019 by Phismith (Talk | contribs)

Jump to: navigation, search

Date: October 23-24, 2019


Protein Informatics Resource
Georgetown University Medical Center
3300 Whitehaven Street, NW, Suite 1200
Washington, DC 20007, USA


The goals of this meeting are:

  • 1. To plan the future of the PRO
  • 2. To foster PRO's collaborations with other initiatives

Schedule: Wednesday, October 23, 2019

8:30 Breakfast

PRO as a framework for advancing disease understanding

Chair: Darren Natale

9:00 Introduction
General introduction to PRO (Darren Natale)
Protein aggregates here? (Alexander Diehl)
PRO sites (Alan Ruttenberg)
10:30-10:45 Break

Disease mechanisms: connecting clinically-relevant protein sequence variations with their impact on underlying molecular mechanisms

Chair: Judith Blake

10:45 Mouse models of human disease (TBD)
11:15 Standardizations
UniProt (Alexander Bateman)
UniProtKB's molecular impact information (Harold Drabkin?)
Disease Ontology (Melody Swan)
Ontology for General Medical Science (Barry Smith)
Discovering molecular mechanisms underlying disease (Karen Ross, Natarajan Kannan)
12:30-13:30 Lunch

17:30 Close of Day 1
18:00 Working dinner

Schedule: Thursday, October 24, 2019

8:15 Breakfast

Clinical discovery: connecting clinically-relevant information to proteoforms and complexes

Chair: Peter d'Eustachio

8:45Connecting proteins to disease using disease pathways (Peter d'Eustachio)
Drug targets (Stephan Schürer)
Connecting antibodies to epitopes and proteins (Randi Vita)
10:30-11:00 Break

Cell type discovery: connecting proteoform expression profiles with clinically-relevant cell types

Chair: Alexander Diehl

11:00 Introduction (Alexander Diehl)
scRNA from KPMP (Oliver He)
Proteoform-based cell type dictionary (Alex Diehl)

12:30-1:30 Lunch
13:30 Working Session (on Grant Proposal)
15:00 Close


Alexander Bateman (EBI)*
Alexander Diehl (Buffalo)
Cecilia Arighi (Delaware / PRO)
Judith Blake (JAX)
Peter d'Eustachio (NYU)
Alexander Diehl (Buffalo)
Harold Drabkin (JAX)
Yongqun (Oliver) He (Michigan)
Natarajan Kannan (Georgia)
Richard LeDuc (Northwestern)
Birgit Meldal (EBI)*
Darren Natale (Georgetown)
? Li Ni (JAX)
Karen Ross (Georgetown)
Alan Ruttenberg (Buffalo)
Stephan Schürer (Miami)
Barry Smith (Buffalo)
Christian Stoeckert (Penn)
Melogy Swan (Baltimore)
Paul Martin Thomas (Northwestern)
Randi Vita (San Diego)
Cathy Wu (Delaware / PRO)
  • =online

Please contact Barry Smith for further information.


The Protein Ontology Consortium
National Center for Ontological Research