Gamuts

See Charles E. Kahn Jr., MD, MS, Joseph J. Budovec, Cesar A. Lam, Stephen Goth, "An Ontology of Differential Diagnosis in Diagnostic Radiology", presented at 2014 AMIA Translational Summit

Abstract: We created an ontology of 282 differential-diagnosis lists, or “gamuts,” in the domain of gastrointestinal radiology. The model describes 7,042 relationships for causality, subsumption, and synonymy among 3,363 disorders and imaging observations; the ontology’s concepts are annotated with and indexed by RadLex® concepts and SNOMED Clinical Terms®. The ontology is published as a Web Ontology Language (OWL) document. The knowledge representation allows automated reasoning over the ontology and integration with heterogeneous biomedical knowledge resources such as decision support systems, clinical image repositories, and the biomedical literature. This ontology has been applied to create several applications, including a RESTful web service, a web-based, illustrated gamuts reference, and a differential-diagnosis quiz generator. The present work serves as a model for a comprehensive ontology of differential diagnosis in diagnostic radiology.

[1], which provides online reference information to link radiology to other Semantic Web resources. The "gamuts.net" site provides an interactive gamuts reference, an online quiz-question generator, and a visualization tool.