Ontology of Economics
PHI 548 (seminar, 3 credits). Registration number: 24057
This course is cross-listed with BMI 508, which is offered as part of the newly accredited PhD program in UB's Department of Biomedical Informatics
Time: 4:00-6:50pm, Mondays, Fall Semester 2016
Room: Baldy 200-G, UB North Campus
Instructors: Barry Smith (Philosophy) and Werner Ceusters (Biomedical Informatics)
Office hours: BS: by appointment via email; WC: TBA
Course Description
This course provides an introduction to biomedical ontology. It will review how data and information are generated through biological and biomedical experiments and through patient care, and show how ontologies are used in accessing, maintaining and exploiting the results. We will describe how biomedical ontologies are developed and evaluated and provide a comparative critical analysis of the principal current ontology resources. We will also review the major theories, methods and tools for the development of ontologies, and illustrate how these are being used in different areas of biomedical research and healthcare. On completion of this course students will have a thorough understanding of strategies to manage and exploit biomedical data; they will have a knowledge of categorization, of the philosophy of experimentation, of the philosophy of medicine, and of computer-based reasoning with data. The seminar will be highly interactive, featuring debates between Drs Smith and Ceusters and between Smith and Ceusters and the course participants.
All slides and videos will be made available at this link
Recommended background reading
- R. Arp, B. Smith, A. D. Spear, Building Ontologies with Basic Formal Ontology
Recommended background video content
Selections from: [1]
Schedule
8/29/2016 Introduction to Ontology 1: General Overview (BS)
Roots of ontology in
- artificial intelligence (Second Naive Physics Manifesto)
- library science (MeSH)
- Semantic Web (OWL)
- Human Genome Project (Gene Ontology)
9/12/2016 Ontology of Clinical Practice (WC)
Disease vs. diagnosis; Electronic Health Records and other systems and techniques for modeling, representing and maintaining patient data
9/19/2016 Ontology of Experiments (WC, BS)
Part 1: Ontology of Clinical Practice (continued) (WC)
Representing clinical data
Part 2: Ontology of Scientific Research (BS)
Background on philosophy of science
The generation and dissemination of new knowledge through scientific experiments
Biomedical research and clinical trials
The Information Artifact Ontology
Video: Clinical Trial Data Wants to be Free
9/26/2016 Introduction to Ontology 2: Ontology in Buffalo (BS)
Includes a presentation by Alex Diehl on the Cell and Protein Ontologies
- Building Ontologies with Basic Formal Ontology
- Open Biomedical Ontologies (OBO) Foundry
- Information Artifact Ontology
- Referent Tracking
- Logical development of the Cell Ontology
- The Cell Ontology 2016
- Protein Ontology: a controlled structured network of protein entities
10/3/2016 Ontology of Social Entities (BS)
Ontology of obligations
Speech act theory
Patient consent
Healthcare organizations
10/10/2016 How to Build an Ontology (BS/WC/NO)
Principles of ontology building (BS) Slides
Further principles of ontology building (WC) Slides
First look at Protégé (NO)
Interactive session (WC/NO/BS)
Target text for interactive session:
- Mary Ceusters, a 54 year old non-smoking female, arrives at a Buffalo General Hospital on August 12th, 2007 and Nurse Smith takes her blood pressure and records 160/90mmHg. Based on this reading, Nurse Smith concludes Mary has high blood pressure and prescribes the drug Bumetanide. On July 11, 2009, Mary Ceusters arrives at Erie County Medical Center complaining of sudden chest pains and Doctor Searle conducts an external examination and concludes Mary has suffered a heart-attack, which he suspects is likely the result of coronary artery disease exacerbated by hypertension.
10/17/2016 Ontology, Logic and Software (WC/AR)
Diagnosis, misdiagnosis, lucky guess, hearsay, and more (WC)
Language vs. Ontology (AR)
What is a ((Health)Care) Process? We have the words. But they are used casually and ambiguously. How do we sort this out? (AR)
The Web Ontology Language (OWL): What it is and how to relate it to Ontology. A quick introduction to OWL including problems when OWL is used to build ontologies (AR)
10/24/2016 Representing Types and Representing Instances (WC)
Introduction to Referent Tracking (WC)
Application of Referent Tracking to deal with Errors in Databases (WC)
10/31/2016 Overview of Ontology: BFO, GO, OBO Foundry (BS)
History and current theoretical foundations for the development of effective biomedical ontologies
- The OBO Foundry: Coordinated Evolution of Ontologies to Support Biomedical Data Integration
- Ontological Realism as a Methodology for Coordinated Evolution of Scientific Ontologies
11/7/2016 Ontology and Terminology (WC / AR)
The Ontology for Oral Health and Disease (OHD) (AR)
Ontology and Terminology: An Introduction (WC)
11/14/2016 Introduction to SNOMED (WC/NO)
SNOMED: Systematized Nomenclature for Medicine (WC)
11/21/2016 Internet of Things / Concluding Summary (WC/BS)
SNOMED (continued) (WC)
The Internet of Things (Biomedical Applications (WC) Slides
Concluding Summary -- What you should have learned from this class (BS) Slides
Coda on SNOMED (WC) Slides
11/28/2016 Student presentations
- 4:00 James Schuler: The Ontology of Diabetes Camp
- 4:20 Jonathan Blaisure: OMOP
- 4:40 Sarah Mullin: The Ontology of Biological and Clinical Statistics
- 5:00 Francesco Franda: Organizations: An Ontological Approach
- 5:20 Fernanda Farinelli: Ontology of Document Templates
- 5:40 Cameron Bosinski: The Origin of Information
- 6:00 Uriah Burke: The Zika Virus
12/5/2016 Student presentations
- 4:00 Qiuyi Zhang: Understanding Accessibility in Healthcare Facilities
- 4:20 Scott Luan: On the Ontology of (Biomedical) Artifacts
- 4:40 Matthew Hudson: Disease surveillance through the lens of ontology
- 5:00 Ruoyu Yang and Binbin Zhang: Ontology of Materials
- 5:20 Munira Binti Mohd Ali: Additive Manufacturing in Dentistry
- 5:40 Federico Borsotti: Ontologies and Relational Databases
- 6:00 Evan Murphy: Ontology of Mental Illness
