ImmPort

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ImmPort: A Guide for Submitters

Date: October 9-10, 2013

Venue: Rho Federal Systems Division (6330 Quadrangle Dr. Suite 500, Chapel Hill, NC 27517)

Goals: The goals of this meeting are:

  • to provide assistance to actual and potential submitters of data to ImmPort: how to make submission more intuitive and more efficient?
  • to enable interaction between submitters and those charged with managing and improving ImmPort in order to identify problems and opportunities for improvement
  • to improve extraction of data from ImmPort: how can we make ImmPort data more easily discoverable and useful to researchers

Draft Schedule

  • All participants should feel free to propose additional topics for discussion by writing to Barry Smith

Day 1: Wednesday, October 9

8:00 Breakfast

8:45 Ashley Xia (NIAID): Opening Remarks

9:00 Barry Smith (ImmPort / University at Buffalo): A Practical Introduction to ImmPort and to NIH Mandates for Data Sharing and Reuse

-- overview of the goals of ImmPort
-- role of standards and ontologies (1) for data submission (2) for data reuse
-- successes and failures we can learn from

10:00 Break

10:30 Anna Maria Masci: The ImmPort Submission Process. A View From Biology

is in charge of submission of data to ImmPort from the project Multiscale System Immunology. She is Research Scientist, Department of immunology at Duke University. Dr. Masci has worked for more than 15 years in the field of cellular and molecular immunology. She has been involved in studies aimed at characterizing the alterations of T-cells repertoire in patients affected by primary and acquired immune deficiencies. She also investigated the activation programs of human T-cells and monocytes-derived Dendritic cells exposed to pathogen derivatives, including TLRs ligands and HIV-1 envelope glycoprotein. In the last five years, she directed her research interests toward computational biology, with particular focus on ontology development and automatic reasoning, and their application in dynamic modeling and simulation. http://www.linkedin.com/profile/view?id=41459681&trk=nav_responsive_tab_profile


Discussion leader: Barry Smith

Brainstorming on
-- existing data management strategies and software tools to enhance data submission
-- how to make your data discoverable and useable by external researchers

12:00 Lunch

13:00 Jeff Wiser (ImmPort / Northrop Grumman): Training session on submitting data to immPort

-- the need to grow ImmPort's clinical submission area

14:30 Break

15:00 Discussion leader: Jeff Wiser

Brainstorming on identifying pain points in submission and on strategies for improvement

Evening: Dinner

Day 2: Thursday, October 9

8:00 Breakfast

8:30 Barry Smith: Initiating a consensus process for creating useful and usable standards and software approaches which will enhance the ImmPort submission process and guarantee discoverability

8:45 Tasking of break-out groups

the standards should be easy to use by ImmPort submitters,
should be recommendable for incorporation into data

management resources (for instance CTMSs);

be compatible with or derived from existing

standards

9:00 Break-Out Groups (possible areas -- final division to be determined on the basis of user requests):

disease areas (allergy / asthma / transplantation / auto-immune diseases / ...)
datatypes (clinical observations / mechanistic assays / ...)
FDA and other standards (CDISC / ... )
discoverability: what kind of data would you like to find in ImmPort and how would you search for it?

Break-Out Group Leaders:

Lindsay Cowell (UT Southwestern)
Barry Smith
Jeff Wiser
TBD

Each break-out group will

-- review existing standards and software in these areas
-- identify future needs and strategies

11:45 Report back and discuss next steps

12:30 Lunch / Close