PRO Consortium Workshop 2017

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Date: October 11-12, 2017

Venue: Jackson Lab, Bar Habor, Maine


Goals and outcomes

The goals of this meeting are:

  • 1. To contribute to the ontological understanding of phenotype and disease across organisms
  • 2. To advance the treatment of protein-related clinical and translational data from the perspective of consistency, discoverability and support for diagnosis
  • 3. To advance coordination between the Protein Ontology and other protein-related information resources

Desired outcomes are of two sorts:

  • Relating to disease:
We will seek greater clarity as to
- how proteomic information in general and the PRO in particular can help us to understand the relationship between genotype and phenotype, for example in understanding disease etiology
- which relations we should use in linking the protein entities represented in the PRO to disease entities
- which are the important entities on the protein side that need to be linked
  • Relating to PRO's interactions with external resources:
UniProt: Draft of policies/recommendations regarding accession/site tracking for UniProt and PRO
IntAct: Identify points of agreement and discrepancy in curation pipelines and resolve as appropriate. Reach agreements for example on reciprocal links and accession issues


The future development of PRO and of PRO’s role in the Alliance of Genome Resources

Use of Noctua for GO annotation, use of PRO in Noctua

Benefits and limitations of PRO

PRO and PTM knowledge networks

Developing PROs scope for annotating diseases

Schedule: Tuesday, October, 10, 2017

19:00 Informal reception for early arrivals in conference hotel

Schedule: Wednesday, October, 11, 2017

Chair: TBD

8:45

10:30 Break

10:45

12:00 Lunch

Chair: TBD:

12:45

14:00 Close of Plenary Sessions.

14:00 Working group meetings

17:00 Close

Schedule: Thursday, October 12, 2017

Venue: JAX

8:00 Continental breakfast

Chair: TBD GO, PRO and UniProt: How they should work together

9:00 Alex Bateman (EBI)

10:30 Break

10:45

12:30 Lunch

Chair: Cecilia Arrighi

13:30

14:30 Break

14:45

16:00 Close


Participants

Cecilia Arighi (Delaware / PRO)
Erich Baker (Baylor))
Alex Bateman (EBI)
Judith Blake (JAX)
Elissa Chesler (JAX)
? Karen Christie (JAX)
Alex Diehl (Buffalo)
Harold Drabkin (JAX)
? Gang Fu (NCBI / NIH)
? John S. Garavelli (Delaware)
? Donna Maglott (NIH / NLM / NCBI)
Darren Natale (Georgetown)
? Veerasamy “Ravi” Ravichandran (NIH / NIGMS)
? Karen Ross (Delaware)
Alan Ruttenberg (Buffalo)
Cynthia Smith (JAX)
Barry Smith (Buffalo)
Kimberley VanAuken (CalTech)
Laurens Wilming (JAX)
Cathy Wu (Delaware / PRO)

Please contact Barry Smith for further information.

Sponsors

The Protein Ontology Consortium
National Center for Ontological Research