Difference between revisions of "PRO Consortium Workshop 2019"

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==Schedule: Wednesday, October 23, 2019==
 
==Schedule: Wednesday, October 23, 2019==
  
''8:30 Breakfast''
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:8:30 Breakfast
  
 
'''PRO as a framework for advancing disease understanding'''
 
'''PRO as a framework for advancing disease understanding'''
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:10:30-10:45 Break
 
:10:30-10:45 Break
  
'''Disease mechanisms: connecting clinically-relevant protein sequence variations with their impact on underlying molecular mechanisms'''
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'''Disease mechanisms: connecting clinically-relevant protein sequence variations with their impact on underlying molecular mechanisms. Part 1'''
 
 
 
''Chair: Judith Blake''
 
''Chair: Judith Blake''
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::UniProt (Alexander Bateman)
 
::UniProt (Alexander Bateman)
 
::UniProtKB's molecular impact information (Harold Drabkin?)
 
::UniProtKB's molecular impact information (Harold Drabkin?)
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 +
:12:30-13:30 Lunch
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'''Disease mechanisms: connecting clinically-relevant protein sequence variations with their impact on underlying molecular mechanisms. Part 1'''
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:13:30
 
::Disease Ontology (Melody Swan)
 
::Disease Ontology (Melody Swan)
 
::Ontology for General Medical Science (Barry Smith)
 
::Ontology for General Medical Science (Barry Smith)
 
:Discovering molecular mechanisms underlying disease (Karen Ross, Natarajan Kannan)
 
:Discovering molecular mechanisms underlying disease (Karen Ross, Natarajan Kannan)
 
:12:30-13:30 Lunch
 
 
  
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:15:30-16:00 Break
 
 
 
 
 
:17:30 Close of Day 1
 
:17:30 Close of Day 1

Revision as of 20:57, 19 August 2019

Date: October 23-24, 2019

Venue:

Protein Informatics Resource
Georgetown University Medical Center
3300 Whitehaven Street, NW, Suite 1200
Washington, DC 20007, USA


Goals

The goals of this meeting are:

  • 1. To plan the future of the PRO
  • 2. To foster PRO's collaborations with other initiatives

Schedule: Wednesday, October 23, 2019

8:30 Breakfast

PRO as a framework for advancing disease understanding

Chair: Darren Natale

9:00 Introduction
General introduction to PRO (Darren Natale)
Protein aggregates here? (Alexander Diehl)
PRO sites (Alan Ruttenberg)
10:30-10:45 Break

Disease mechanisms: connecting clinically-relevant protein sequence variations with their impact on underlying molecular mechanisms. Part 1

Chair: Judith Blake

10:45 Mouse models of human disease (TBD)
11:15 Standardizations
UniProt (Alexander Bateman)
UniProtKB's molecular impact information (Harold Drabkin?)
12:30-13:30 Lunch

Disease mechanisms: connecting clinically-relevant protein sequence variations with their impact on underlying molecular mechanisms. Part 1

13:30
Disease Ontology (Melody Swan)
Ontology for General Medical Science (Barry Smith)
Discovering molecular mechanisms underlying disease (Karen Ross, Natarajan Kannan)
15:30-16:00 Break
17:30 Close of Day 1
18:00 Working dinner

Schedule: Thursday, October 24, 2019

8:15 Breakfast

Clinical discovery: connecting clinically-relevant information to proteoforms and complexes

Chair: Peter d'Eustachio

8:45Connecting proteins to disease using disease pathways (Peter d'Eustachio)
Drug targets (Stephan Schürer)
Connecting antibodies to epitopes and proteins (Randi Vita)
10:30-11:00 Break

Cell type discovery: connecting proteoform expression profiles with clinically-relevant cell types

Chair: Alexander Diehl

11:00 Introduction (Alexander Diehl)
scRNA from KPMP (Oliver He)
Proteoform-based cell type dictionary (Alex Diehl)


12:30-1:30 Lunch
13:30 Working Session (on Grant Proposal)
15:00 Close

Participants

Alexander Bateman (EBI)*
Alexander Diehl (Buffalo)
Cecilia Arighi (Delaware / PRO)
Judith Blake (JAX)
Peter d'Eustachio (NYU)
Alexander Diehl (Buffalo)
Harold Drabkin (JAX)
Yongqun (Oliver) He (Michigan)
Natarajan Kannan (Georgia)
Richard LeDuc (Northwestern)
Birgit Meldal (EBI)*
Darren Natale (Georgetown)
? Li Ni (JAX)
Karen Ross (Georgetown)
Alan Ruttenberg (Buffalo)
Stephan Schürer (Miami)
Barry Smith (Buffalo)
Christian Stoeckert (Penn)
Melogy Swan (Baltimore)
Paul Martin Thomas (Northwestern)
Randi Vita (San Diego)
Cathy Wu (Delaware / PRO)
  • =online


Please contact Barry Smith for further information.

Sponsors

The Protein Ontology Consortium
National Center for Ontological Research